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Mari Cleide Sogayar

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Mari Cleide Sogayar – Productivity fellowship/research award (CNPq Level 1A ) 1968: BS in Biological Sciences (University of São Paulo Biosciences Institute); 1973: Master´s degree (MsSci University of California San Diego, Biology Dept.), 1977: PhD in Biochemistry (University of São Paulo Chemistry Institute); 198201984: Visiting Assistant Professor (Harvard Medical School, Dana Farber Cancer Institute). 1980: University of São Paulo Chemistry Institute (Assistant Prof.) 1987: University of São Paulo Chemistry Institute (Associate Prof.) 2000 – 2013: Biochemistry Dept., University of São Paulo, Chemistry Institute (Full Professor) 2013 present: Internal Medicine Dept., University of São Paulo, Medical School (Senior Professor) Research area: Biochemistry, with emphasis in Cell Biology, Molecular Biology and Biotechnology. Research themes: a)cell proliferation control and the origin of neoplasia, using genomics, transcriptomics, functional genomics and proteomics; b)stem cells differentiation aiming at tissue regeneration and repair; c)cell therapy based on both adult and stem cells applied to degenerative diseases (clinical human pancreatic islet transplantation in hyperlabile type 1 diabetic patients) and tissue engineering; d)production of recombinant proteins in heterologous expression systems (bacteria, mammalian cells and the baculovirus/insect cells system) for production of recombinant biopharmaceuticals, such as: human prolactin, human leptin, human and bovine follicle stimulating hormone-FSH, human amylin/IAPP, human clotting factors (FVIII, FIX and von Willebrand), human Bone Morphogenetic Proteins-BMPs for bone repair, human platelet-derived growth factor PDGF, human vascular endothelial growth factors VEGFs, human basic fibroblast growth factor hbFGF, human granulocyte and granulocyte and macrophage colony-stimulating factors hG- and hGM-CSFs, hR-Spondin, among others. e)Supervised 41 PhD and 14 MsSci students and more than 30 post-doctoral fellows; offered training to over 40 undergraduate students. f)Coordinates the activities of the Cell and Molecular Therapy translational research Center (NUCEL) of the University of São Paulo ( (Text informed by the author)